• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Hermetic, piercing without needle and automatically resealable connector, for devices to be used to collect and administer liquid solutions for pharmaceutical and / or nutritional use. One connector (1) for devices used to collect and administer liquid solutions for pharmaceutical and / or nutritional use. The connector comprises a plug (7) that can be pierced by pressing a needle-free tongue (18) for introduction / collection. The plug (7) comprises a check valve with lockable tabs (9) which are opened by introducing said tongue (18) and which are resiliently closed after removal of the inserted tongue and additionally comprising a perforably resealable membrane (11) resiliently arranged to tightly close the inlet end of said check valve. Said closing flaps (9) are located at one end of a body (30) made of elastically deformable plastic material, which is traversed longitudinally by a slit of rectangular section (10), the slit being closed at the other end by said membrane (11 ) pierceable and resiliently resilient.
    公开号:BR112013019152B1
    申请号:R112013019152-0
    申请日:2012-01-24
    公开日:2020-11-17
    发明作者:Paolo Giuseppe Gobbi Frattini
    申请人:Paolo Gobbi Frattini S.R.L.；
    IPC主号:
    专利说明:

    [001] The present invention relates to an airtight, piercing without needle and automatically resealable connector, for devices to be used to collect and administer liquid solutions for pharmaceutical and / or nutritional use.
    [002] In all medical devices used to administer liquid solutions for pharmaceutical and / or nutritional use, the connections between the various parts to be connected for various purposes, such as the administration and collection of liquids, creation of circulation circuits etc. , are of fundamental importance.
    [003] In particular, packaging to contain liquid solutions for pharmaceutical and / or nutritional use, in which flexible tubes used to introduce additional substances and / or collect the solution contained in the packaging, are already known.
    [004] Such flexible tubes are closed by means of hermetically sealed connectors, which must be additionally drilled for administration and collection purposes and then be hermetically resealed at the end of the operation.
    [005] In particular, the connectors for the aforementioned use which comprise a thermoplastic body are already known, such connectors can be pierced with the needle of a syringe.
    [006] Connectors that do not require a needle because they are closed by a plastic body that can slide into a closed position to establish communication between the syringe fitting with a screw tip (Luer lock type) or similar and the inside of the flexible tube they are also known.
    [007] Finally, connectors that can be opened without a needle are known, for example, through the US patent application US 2008/093571, the international patent application WO95 / 15194 and the US patent 5,268,771, whose connectors they are provided with a plug formed by a deformable plastic body, crossed longitudinally by a slit in which a syringe with Luer nozzle is inserted to determine the provisional opening of an elastically deformable check valve, which closes automatically when the luer nozzle retracts after introduction or collection operation.
    [008] All these known solutions present problems that include, respectively, the need for a syringe with a needle, which can cause accidental injuries, non-hermetic closure before use, flawed closure after the first opening operation, the cost relatively high, among others.
    [009] In view of the state of the art, the present invention aims to provide a connector that, starting from a state of hermetically sealed, can be pierced without a needle to perform an operation to introduce and collect the liquid and that can then be resealed after the end of the operation.
    [0010] The present invention allows to achieve this goal by means of a pierceable plug by pressing a needle-free insertion / collection tongue (such as the luer tip of a syringe), in which the plug comprises a check valve with lockable flaps that are opened when introducing said tongue and closing again elasticly after removing the introduced tongue, characterized by the fact that said plug additionally comprises a perforable and elastically resealable membrane arranged to hermetically close the inlet end of said retraction valve.
    [0011] By means of the present invention, important advantageous effects are obtained, such as the hermetic closure before use, the resealable safety closure after each operation of introducing and extracting the introduction / collection tongue, the elimination of any backflow effect when the tongue is extracted, the low cost, and the absence of needles.
    [0012] An embodiment of the present invention is shown by way of an example for illustrative purposes in the attached drawings, in which: - figure 1 shows an axial section of the connector according to the invention; figure 2 shows a top view of the plug of said connector with respect to figure 1; figure 3 shows a bottom view of said plug with respect to figure 1; figure 4 shows a view of the section of said plug taken along line IV-IV in figure 1; - figure 5 shows the entry end of the connector in the axial section completed with a removable protective cover; figure 6 shows a connector similar to figure 1 and a syringe before its connector punctures the connector plug; - figure 7 shows the connector and the syringe on an enlarged scale after fitting; - figure 8 shows an axial section of the same connector after the syringe detaches; figure 9 shows a top plan view of the connector of figure 8; and - figures 10 to 13 show some methods of using the connector according to the invention.
    [0013] The connector shown in figures 1 to 4, which is indicated as a whole with the number 1, comprises a main body 2, preferably made of polypropylene carbonate, and is crossed by an axial hole 3. The main body 2 consists of a collar 4 and an axial extension 5.
    [0014] A support 6 made of polypropylene polycarbonate is affixed to the collar 4 for a plug 7 made of an elastically deformable plastic material, in particular SEBS TPE polyisoprene silicone, and an annular ring 8 is fixedly arranged around the support 6.
    [0015] The plug 7 includes a body 30 and a pair of side flaps 9 which gradually decrease between which a slit of thin rectangular section 10 is formed, preferably during the molding step, said slit is opened at the bottom end and extends to the top just before a thin membrane for airtight closure 11 made in one piece with the rest of the plug 7.
    [0016] It should be noted that the sum of the slit length (10) and the thickness of the membrane (11) is less than the length of a syringe tip.
    [0017] The two side flaps 9 include external concave recesses 12, which project laterally from the lower edge of said flaps, starting at the slot 10. An upper collar 13 is disposed on the upper portion of the support 6.
    [0018] If necessary, a protective plug 14 can hang over the holder 6 and the plug 7, as shown in figure 5. Easily breakable connection points 15 keeps the plug 14 in position within the annular ring 8 before first use connector 1.
    [0019] The materials of its components are duly subjected to antimicrobial treatment due to the use that will be given to the connector. In particular, the use of silver ions may be provided, which bind to the cell wall by penetrating through it, thereby obstructing the duplication of cellular DNA and inhibiting the respiration of microbes. Alternatively, the use of ionic plasma can also be provided.
    [0020] Figure 6 shows a container 1 such as that of figures 1 to 4, without the lid 14 and with the axial extension 5 engaged in a flexible tube 16 for the introduction or collection of liquids in or of a containment device. Under this condition, the membrane 11 tightly closes the plug 7, preventing any amount of liquid from leaving or entering the axial hole 3. A syringe 17 with the luer nozzle or connecting tongue 18 is ready to connect to the tube 16 via the connector 1.
    [0021] The connection is made by pressing the luer nozzle 18 against the upper portion of the plug 7. Thus, the luer nozzle 18 perforates the membrane 11 and is inserted into the slot 10, separating the two side flaps 9 to reach the entrance of the axial hole 3, as shown in figure 7.
    [0022] Considering that, as mentioned, the total axial height of the slot 10 and the membrane 11 is less than the length of the luer nozzle of a syringe, the luer nozzle 18 introduced in this way allows the syringe 16 to operate in two ways allowing thus the introduction and collection of liquids through the flexible tube 16.
    [0023] The syringe can also be of the type known as "Luer lock", that is, with the male tip partially enclosed by an internally threaded external coaxial socket (indicated by a dashed line and with the number 31 in figure 6). In this case, the insertion of the luer nozzle 18 occurs by screwing the outer sleeve 31 of the syringe into the holder 6 of the plug 7, using an external groove 32 of the holder 6 for this purpose (figure 7).
    [0024] At the end of the operation, the luer nozzle 18 of the syringe can be extracted from the slot 10 of the plug 7, whose side flaps close by means of elastic force, reaching the position of figure 8, identical to the original position of figure 1. A membrane 11 also closes elastically, thus obtaining the hermetic resealing of the connector, as shown in figure 9, where the dashed and dotted line 19 symbolizes the point of recontact and closing of the membrane.
    [0025] The concave shape of the external recesses 12 of the side flaps 9 facilitates and forces the closure of the slit 10 and the membrane 11, thus obtaining the function of the check valve that prevents the liquid from remaining in the flexible tube 16 during and after the extraction the luer nozzle.
    [0026] Figures 10 to 13 show methods of using the connector according to the invention. In particular, figure 10 shows its application in a flexible tube of introduction / collection of a flexible container containing liquid pharmaceutical and / or nutritional solutions and figure 11 shows the combination of said connector with a fitting member 21 to connect to the mouth a bottle 22 for liquid or powder solutions. Figure 12 shows the association of a connector according to the invention to an infusion tube 23 with a side connection and Figure 13 shows the association of said connector with a plug member 24 for infusion devices 25 of various types.
    [0027] Please note that the locking member 24 is of the type described in European patent EP 1004329, that is, it is formed by two parts 26 and 27 that rotate in relation to each other to allow a threaded connection of the locking member to the device infusion 25 without the need to rotate the part to be used for the insertion of the luer nozzle of the syringe.
    权利要求:
    Claims (16)
    [0001]
    1. Connector (1) for devices used to collect and administer liquid solutions for pharmaceutical and / or nutritional use, comprising a pierceable plug (7) by pressing on a tongue without an introduction / collection needle (18), in which the plug (7) ) comprises a check valve with lockable tabs (9) which can be opened by introducing said tongue (18) and which are elastically closed again after removing the tongue that was introduced, in which said plug (7) is formed by a body single (30) made of elastically deformable material, which is partially pierced longitudinally by a slit of thin rectangular section (10), which is opened at a lower end in order to form said lockable flaps (9) and is closed at the upper end by a thin membrane (11) that is perforable and elastically resealable, made in a single piece with said single body (30), characterized by the fact that the bottom face of the single body (30) is provided with concave recesses and external (12) extending laterally with increasing concavity from the lower end of the closing flaps (9) towards the lateral surface of the single body (30).
    [0002]
    2. Connector according to claim 1, characterized in that the sum of the length of said slot (10) and the thickness of said membrane (11) is less than the length of the luer nozzle of a syringe.
    [0003]
    Connector according to claim 1 or 2, characterized in that said body (30) of elastically deformable material is made of SEBS TPE polypropylene silicone.
    [0004]
    Connector according to any one of the preceding claims, characterized by the fact that said slot (10) is formed during the molding step of said single body (30).
    [0005]
    5. Connector according to any one of the preceding claims, characterized in that said body (30) of elastically deformable material is located within a support (6) fixed on a main body (2) crossed by an axial hole (3 ).
    [0006]
    6. Connector according to claim 5, characterized in that said support (6) is provided with an external groove (32) that serves to thread the socket on the outer end of a luer-type syringe.
    [0007]
    7. Connector according to claim 6, characterized by the fact that said main body (2) has an axial extension (5) that serves to insert a flexible tube (16), to introduce or collect a liquid, or a device containment.
    [0008]
    Connector according to any one of claims 5 to 7, characterized by the fact that it comprises a cover (14) superimposed and connected by easily breaking points (15) to said main body (2) to protect said plug (7) before the first use of the connector (1).
    [0009]
    Connector according to any one of claims 5 to 8, characterized in that said support (6) and said main body (2) are made of polypropylene polycarbonate.
    [0010]
    10. Connector according to any one of the preceding claims, characterized by the fact that all its components are subjected to antimicrobial treatment.
    [0011]
    11. Connector according to claim 10, characterized by the fact that said antimicrobial treatment is based on silver ions.
    [0012]
    12. Connector according to claim 10, characterized by the fact that said antimicrobial treatment is carried out with ionic plasma.
    [0013]
    13. Connector according to any one of the preceding claims, characterized by the fact that it is applied in a flexible tube to introduce and collect in / from a flexible container (20) containing a liquid solution for pharmaceutical and / or nutritional use.
    [0014]
    14. Connector according to any one of the preceding claims, characterized in that it is applied to a fitting member (21) that serves to engage the mouth of a bottle (20) for liquid or powder solutions.
    [0015]
    15. Connector according to any of the previous claims, characterized by the fact that it is applied in a line with lateral fixation.
    [0016]
    16. Connector according to any of the preceding claims, characterized by the fact that it is applied to a member of fitting (24) for lines of various types, wherein said fitting member (24) is composed of two parts (26, 27) that rotate with each other.
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    法律状态:
    2018-03-13| B25A| Requested transfer of rights approved|Owner name: PAOLO GOBBI FRATTINI S.R.L. (IT) |
    2018-12-18| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2020-03-03| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2020-08-04| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2020-11-17| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/01/2012, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    ITMI2011A000101A|IT1403656B1|2011-01-28|2011-01-28|HERMETIC CLOSURE CONNECTOR, PERFORTABLE WITHOUT NEEDLE AND AUTOMATICALLY CLOSABLE FOR TIGHTENING, FOR FLEXIBLE PIPES INTENDED FOR THE COLLECTION AND DISTRIBUTION OF LIQUID SOLUTIONS FOR PHARMACOLOGICAL AND / OR NUTRITIONAL USE.|
    ITMI2011A000101|2011-01-28|
    PCT/EP2012/051008|WO2012101101A1|2011-01-28|2012-01-24|Hermetic connector, pierceable without needle and automatically and sealingly reclosable, for devices intended for collecting and dispensing liquid solutions for pharmaceutical and/or nutritional use|
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